BD-2, beta-Defensin 2, human

£114.00 exc. VAT

5ug

SKU: RC220-13.SIZE.5ug Category:

BD-2, beta-Defensin 2, human: Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, four human β-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36 a.a.), a propeptide region. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. β-Defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues. UnitProt ID: O15263

CAS
Grade
HS Code

2937.19.0000

Manufacturer

Bio Basic

Pack Size

5ug

Shipping Conditions

ICE

Sterile

yes

Storage Conditions

(-15 to -20)C

UNSPSC Category

Other Enzymes

UNSPSC Code

12352202

DG
Hazard Class
Hazard UN
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