Retinoblastoma-Associated Protein Fragment (137 a.a.)

£114.00 exc. VAT

10ug

SKU: RC712-20.SIZE.10ug Category:

Retinoblastoma-Associated Protein Fragment (137 a.a.): Members of the Hedgehog (Hh) family are highly conserved proteins which are widely represented throughout the animal kingdom. The three known mammalian Hh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh) are structurally related and share a high degree of amino-acid sequence identity (e.g., Shh and Ihh are 93% identical). The biologically active form of Hh molecules is obtained by autocatalytic cleavage of their precursor proteins and corresponds to approximately the N-terminal one half of the precursor molecule. Although Hh proteins have unique expression patterns and distinct biological roles within their respective regions of secretion, they use the same signaling pathway and can substitute for each other in experimental systems. Recombinant E. coli derived Human Sonic HedgeHog is a 20.0 kDa protein consisting of 176 amino acid residues, including an N-terminal Ile-Val-Ile sequence substituted for the natural occurring chemically modified Cys residue.

CAS
Grade
HS Code

2937.19.0000

Manufacturer

Bio Basic

Pack Size

10ug

Shipping Conditions

ICE

Sterile

yes

Storage Conditions

(-15 to -20)C

UNSPSC Category

Other Proteins

UNSPSC Code

12352202

DG
Hazard Class
Hazard UN
Shopping Basket
Scroll to Top